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Hepatic abscess due to Eikenella corrodens and Streptococcus milleri: implications for antibiotic therapy
D Quinlivan1, T M Davis, F J Daly
1University of Western Australia, Department of Medicine, Fremantle, Western Australia.
The Journal of Infection
|July 1, 1996
Abstract:
We report a case of intrahepatic abscess involving infection with Eikenella corrodens. The organism proved difficult to isolate and would not have been covered by some empirical regimens used in penicillin-allergic patients.
Insights
A rare intrahepatic abscess caused by Eikenella corrodens infection was identified. This bacterium is challenging to detect and may evade common antibiotic treatments for penicillin-allergic individuals.
Area of Science:
- Microbiology
- Infectious Diseases
- Hepatology
Background:
- Intrahepatic abscesses are serious liver infections.
- Eikenella corrodens is an unusual pathogen in hepatic abscesses.
- Accurate identification of causative agents is crucial for effective treatment.
Observation:
- A case of intrahepatic abscess was observed.
- The abscess was infected with Eikenella corrodens.
- Eikenella corrodens presented diagnostic challenges.
Findings:
- Eikenella corrodens was difficult to isolate from the abscess.
- The organism is not typically covered by standard empirical antibiotic regimens for penicillin-allergic patients.
- This highlights a potential gap in empirical treatment strategies.
Implications:
- Clinicians should consider Eikenella corrodens in intrahepatic abscess cases, especially when standard cultures are negative or treatment fails.
- Diagnostic laboratories should be aware of the fastidious nature of Eikenella corrodens.
- Treatment guidelines for intrahepatic abscesses may need revision to include coverage for less common pathogens like Eikenella corrodens, particularly in specific patient populations.
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