[Dynamics of changes in anomalous human cells during prolonged cultivation in the stationary phase. Trisomy 7 cells]

Ontogenetic changes of normal diploid cells and cells with chromosomal aberration (strain LHC-162; 47, XY, +7) were studied in prolonged cultivation in stationary phase. Cultivated cells were human found to possess their specific type of ontogenetic changes for each culture; the dynamics of these changes depended on the density of cellular population. Two morphologically different cellular subpopulations differing by the degree of cell nucleus heterochromatinization (normal strains) and three different cellular subpopulations in the aberrant strain (47, XY, +7) were discovered in studying the cell nucleus.