A molecular model for human Big-Endothelin-1 (Big ET-1)
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1Department of Crystallography, Birkbeck College, University of London, UK.
FEBS Letters
|September 30, 1996
Abstract:
A molecular model has been developed for human Big Endothelin-1, which is the immediate precursor to the potent vasoconstrictor polypeptide endothelin-1 and the target of the highly specific endothelin converting enzyme. This model is produced by a threading algorithm protocol and is consistent with all the currently available structural and biochemical data for this molecule.