In vitro load measurement using an instrumented spinal fixation device
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Updated: Nov 4, 2026

In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
A Rohlmann1, L H Riley, G Bergmann
1Biomechanics Laboratory, Orthopaedic Hospital, Free University of Berlin, Germany.
Abstract:
An AO spinal fixateur interne was modified to study the effects of a corpectomy on implant performance. A hermetically sealed cartridge containing strain gauges and an inductively powered telemetry unit was integrated into the threaded portion of the original implant. Five cadaveric spines were instrumented with the modified implant spanning a single lumbar vertebra. The spines were tested in axial compression, torsion, flexion, extension and lateral bending. Measurements of the three forces and moments within the implant were performed in the intact spine and repeated following a corpectomy and corpectomy plus complete posterior ligamentous injury. The bending moment, increased following corpectomy in all testing modes. The largest increase was in the flexion bending moment, which increased from 155 Nmm to 3328 Nmm following corpectomy.

