Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antioxidant vitamins and immunodeficiency

P Mastroiacovo1, C Ajassa, G Berardelli

  • 1Institute of General Physiology, La Sapienza University, Rome, Italy.

International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patients with cancer who will be cured and projections of complete prevalence in Italy from 2018 to 2030.

ESMO open·2024
Same author

Detection and full genomic sequencing of rare hepatitis E virus genotype 4d in Italian wastewater, undetected by clinical surveillance.

The Science of the total environment·2023
Same author

Epidemiological and molecular characterization of HBV and HCV infections in HIV-1-infected inmate population in Italy: a 2017-2019 multicenter cross-sectional study.

Scientific reports·2023
Same author

Preliminary data on the neurophysiological evaluation of male sexual dysfunction in patients with pelvic ring fractures: a multicenter retrospective study.

European review for medical and pharmacological sciences·2023
Same author

The neutrophil/lymphocyte ratio as a prognostic factor in COVID-19 patients: a case-control study.

European review for medical and pharmacological sciences·2022
Same author

Optimization methods for the imputation of missing values in Educational Institutions Data.

MethodsX·2021

Children with HIV infection often experience deficiencies in key antioxidant vitamins like vitamin E and beta-carotene. This study highlights hypovitaminosis as a significant issue alongside known immune and blood alterations in pediatric HIV.

Area of Science:

  • Pediatric immunology
  • Nutritional science
  • Infectious diseases

Background:

  • Human Immunodeficiency Virus (HIV) infection in children is associated with significant health complications.
  • Known complications include alterations in hematological parameters and immune function.
  • The impact of HIV on vitamin status, particularly antioxidant vitamins, requires further investigation in pediatric populations.

Purpose of the Study:

  • To investigate the levels of key antioxidant vitamins (vitamin E and beta-carotene) in the plasma of children with HIV infection.
  • To assess the relationship between HIV status and vitamin status in this age group.
  • To identify potential nutritional deficiencies contributing to disease progression or complications.

Main Methods:

  • Plasma samples were collected from 20 children aged 1 to 6 years diagnosed with HIV infection.

Related Experiment Videos

  • Vitamin assays were performed to quantify levels of vitamin E and beta-carotene.
  • Hematochemical and immunoassay analyses were conducted to evaluate overall health status.

    • Main Results:

    • Children with HIV exhibited alterations in both hematochemical and immune profiles.
    • A significant state of hypovitaminosis was identified, specifically involving crucial antioxidant vitamins.
    • Reduced levels of vitamin E and beta-carotene were observed in the plasma of seropositive children.

    Conclusions:

    • Pediatric HIV infection is linked to hypovitaminosis of essential antioxidant vitamins.
    • These vitamin deficiencies represent an additional comorbidity in children with HIV, beyond immune and hematological changes.
    • Addressing antioxidant vitamin status may be important for managing pediatric HIV infection.