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FRAXA premutation associated with premature ovarian failure
A M Vianna-Morgante1, S S Costa, A S Pares
1Departamento de Biologia, Universidade de São Paulo, Brazil.
American Journal of Medical Genetics
|August 9, 1996
Abstract:
A family is described in which six females in three generations experienced premature ovarian failure (POF). In three of them a FRAXA premutation was documented and the carrier status of a fourth female could be inferred, because her son had the fragile X syndrome. These findings provide further evidence for a nonrandom association between POF and the FRAXA premutation.