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Epileptic attacks associated with wasp sting-induced anaphylaxis
M A Gonzalo Garijo1, P Bobadilla González, J Puyana Ruiz
1Allergology Department, Infanta Cristina University Hospital, Badajoz, Spain.
Summary
A patient experienced epileptic seizures linked to anaphylactic shock from wasp venom. Wasp venom immunotherapy proved effective, suggesting seizures were due to anaphylaxis complications like hypotension.
Area of Science:
- Allergy and Immunology
- Neurology
Background:
- Anaphylaxis, a severe allergic reaction, can have varied clinical presentations.
- Epileptic seizures are a rare but reported complication of anaphylaxis.
Observation:
- A patient with no prior allergies experienced two episodes of anaphylactic shock following wasp stings.
- Each episode was associated with an epileptic attack.
- Immunological testing confirmed IgE-mediated hypersensitivity specifically to Polistes spp. wasp venom.
Findings:
- Specific IgE levels against Polistes spp. venom were elevated (0.86 kU/I), and intradermal tests were positive.
- Tests for Vespula spp. and Apis mellifera venoms were negative.
- Wasp venom immunotherapy was highly effective in preventing further reactions.
Implications:
- This case highlights a rare association between wasp venom-induced anaphylaxis and epileptic seizures.
- The seizures are likely secondary to anoxemia from anaphylaxis-induced hypotension and cardiovascular effects.
- Effective immunotherapy can prevent severe allergic reactions and associated neurological complications.