Periauricular eczematization in childhood atopic dermatitis
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Published on: March 24, 2023
1Department of Dermatology, Seoul National University College of Medicine, Korea.
Insights
Periauricular eczematization (PAE) is common in children with atopic dermatitis (AD) in Korea, often linked to Staphylococcus aureus. Topical antibiotics effectively treat these ear lesions.
Area of Science:
- Dermatology
- Pediatrics
- Microbiology
Background:
- Atopic dermatitis (AD) is a common inflammatory skin condition in children.
- Periauricular eczematization (PAE) is a specific manifestation observed around the ears.
- The role of Staphylococcus aureus in PAE requires further investigation.
Purpose of the Study:
- To determine the prevalence of PAE in Korean children with AD.
- To evaluate the clinical significance and treatment of PAE.
- To explore the potential pathogenetic role of Staphylococcus aureus in PAE.
Main Methods:
- A study involving 107 children diagnosed with atopic dermatitis.
- Classification of PAE into infraauricular and postauricular fissuring.
- Bacterial cultures from ear lesions and assessment of treatment response to topical erythromycin.
Main Results:
- PAE, specifically infraauricular and postauricular fissures, was observed in 64.5% of children with AD, significantly higher than controls (1.3%).
- Staphylococcus aureus was identified in 12 of 14 oozing infraauricular fissures.
- Topical erythromycin cream showed faster and more effective improvement of ear lesions.
Conclusions:
- Periauricular eczematization is a characteristic clinical finding in pediatric atopic dermatitis.
- Staphylococcus aureus likely plays a role in the pathogenesis of PAE.
- Topical antibiotics are a recommended treatment for managing PAE in children with AD.
Abstract:
We investigated the prevalence of periauricular eczematization (PAE) in children with atopic dermatitis (AD) in Korea, and evaluated the clinical significance of the lesion in terms of its treatment in relation to a possible pathogenetic role for Staphylococcus aureus. Tentatively, PAE was classified as infraauricular and postauricular fissuring, which were observed in 62 (57.9%) and 37 (34.6%) of 107 patients, respectively. Sixty eight patients (64.5%) had infraauricular or postauricular fissures, or both, and this prevalence was significantly (p < 0.01) higher than that in controls (1.3%). Staphylococcus aureus was cultured from oozing material from infraauricular fissures in 12 of 14 patients, and topical application of erythromycin cream to the ear lesions led to faster and more definite improvement. Our study shows that PAE is a characteristic clinical manifestation of AD, probably induced by S. aureus. Topical antibiotics are worth trying for effective management of this disorder.
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