Distribution of the HLA-DQA1 polymorphism in the population of the Basque Country (Spain)
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B Esparza1, C Pestoni, M D Martin
1Facultad de Medicina y Odontología, Universidad del País Vasco, Leioa, Vizcaya, Spain.
Gene Geography : a Computerized Bulletin on Human Gene Frequencies
|April 1, 1995
Abstract:
Allele and genotype frequencies at the HLA-DQA1 locus were determined in Basque Country populations using PCR methodology and a dot-blot assay with ASO probes. The results showed no deviation from the Hardy-Weinberg equilibrium. No differences were found between the three Basque Provinces, but gene frequencies were significantly different from those of some other Spanish and world populations.