Autofluorescence in a patient with adult vitelliform degeneration

The case of an 83 year-old woman is presented in whom bilateral vitelliform macular cysts were observed to fluoresce during the pre-injection phase of intravenous fluorescein angiography. This suggests that the vitelliform response is a non-specific event occurring in retinal pigment epithelial disease in which lipofuscin may or may not be manufactured.