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Updated: Aug 5, 2026
11:25
Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
Published on: April 1, 2015
[The characteristics of infectious immunosuppression in patients with benign subleukemic myelosis]
Likars'Ka Sprava
|July 1, 1995
Abstract:
Sixty-five patients with subleukemic myelosis (SLM) during the stage of advanced clinical manifestations were evaluated for parameters characterizing immunologic reactivity. Infectious- inflammatory processes in SLM were found out to develop in the presence of immunity deficiency manifested by the depression of T-and phagocytic link of immunity. Superimposed infection in this pathology promotes further depression of T-link of immunity as well as activation of those cellular parameters characterizing the nonspecific defence.
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01:27Disorders of Leukocytes
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...
01:25Immunodeficiency Diseases
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
There are three main causes of immunodeficiency disorders...