Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

In vivo comparison between two tip pressure transducer systems

A E Aubert1, M Vrolix, H De Geest

  • 1Department of Cardiology, University Hospital Gasthuisberg, Catholic University Leuven, Belgium.

International Journal of Clinical Monitoring and Computing
|May 1, 1995
PubMed
Summary

The Sentron manometer demonstrates strong correlation with the Millar microtip catheter for measuring left ventricular pressure in dogs. This finding suggests the Sentron offers a cost-effective, accurate alternative for cardiovascular research.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

RNA Profiling in Human and Murine Transplanted Hearts: Identification and Validation of Therapeutic Targets for Acute Cardiac and Renal Allograft Rejection.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015
Same author

Dabigatran versus warfarin in patients with mechanical heart valves: reply.

Journal of thrombosis and haemostasis : JTH·2014
Same author

Nonlinear heart rate dynamics: circadian profile and influence of age and gender.

Medical engineering & physics·2011
Same author

Pre-hospital treatment of STEMI patients. A scientific statement of the Working Group Acute Cardiac Care of the European Society of Cardiology.

Acute cardiac care·2011
Same author

Departures from the protocol during conduct of a clinical trial: a pattern from the data record consistent with a learning curve.

Quality & safety in health care·2010
Same author

Effect of endurance training on blood pressure regulation, biomarkers and the heart in subjects at a higher age.

Scandinavian journal of medicine & science in sports·2010

Area of Science:

  • Cardiovascular Physiology
  • Biomedical Engineering
  • Medical Device Technology

Background:

  • Accurate measurement of left ventricular pressure is crucial for diagnosing and managing cardiovascular diseases.
  • Existing pressure measurement tools include fluid-filled catheters, microtip transducer catheters, and newer solid-state sensor catheters.
  • Each technology presents trade-offs in accuracy, cost, and invasiveness.

Purpose of the Study:

  • To compare the in vivo accuracy and performance of the Sentron solid-state catheter against the Millar microtip catheter, a recognized gold standard.
  • To evaluate the correlation of pressure values and their derivatives obtained from both catheter systems.
  • To assess the Sentron catheter's potential as a cost-effective alternative for cardiovascular pressure monitoring.

Main Methods:

Related Experiment Videos

  • Simultaneous in vivo measurements were performed using both Sentron and Millar microtip catheters in the left ventricle of canine models.
  • Left ventricular pressure variations were induced via pharmacological infusion.
  • Data analysis included direct pressure value comparison, calculation of pressure derivatives, and cross-correlation analysis in both time and frequency domains.

Main Results:

  • High correlation coefficients were observed for left ventricular systolic pressure (R=0.992) and positive pressure derivative (R=0.993).
  • Good correlation was also found for end-diastolic pressure (R=0.809), while negative derivative correlation was moderate (R=0.634).
  • Mean cross-correlation between pressure signals was 0.61 ± 0.04, with no significant differences in frequency domain peak analysis.

Conclusions:

  • The Sentron manometer shows a high degree of accuracy and reliability when compared to the Millar microtip catheter for left ventricular pressure measurements in vivo.
  • The Sentron catheter presents a viable, cost-effective alternative to both less accurate fluid-filled catheters and more expensive microtip systems.
  • This study supports the Sentron manometer's utility in cardiovascular research and clinical applications requiring precise pressure monitoring.