Related Experiment Video
Updated: Jul 21, 2026

09:12
Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates
Published on: January 30, 2014
The microglial cell. A historical review
1Department of Neurology, Albany Medical College, NY 12208, USA.
Journal of the Neurological Sciences
|December 1, 1995
Summary
Microglia originate from monocytes and play crucial roles in brain development, injury response, and neuroprotection. These immune cells are vital for maintaining brain health and are implicated in neurodegenerative diseases.
Area of Science:
- Neuroscience
- Immunology
- Cell Biology
Background:
- Modern research confirms microglia originate from circulating monocytes that enter the brain during development.
- Microglia are essential for brain remodeling during maturation and adopt a resting state.
Related Concept Videos
Glial Cells
Overview
Nervous Tissue: Glial Cells
Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial cells that interact...
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial cells that interact...

