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The beta-prism: a new folding motif

T Shimizu1, K Morikawa

  • 1Nara Institute of Science and Technology, Japan. shimizu@bs.aist-nara.ac.jp

A new protein fold with internal symmetry has been observed in two proteins: vitelline membrane outer layer protein I (VMO-I) and delta-endotoxin. Despite lacking any discernible sequence similarity, both proteins have similar three-dimensional structures as well as a carbohydrate-binding site in the top region of the common fold.

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