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Drinking patterns in liver transplant recipients

L E Tripp1, J R Clemons, R R Goldstein

  • 1Department of Psychiatry, Baylor University Medical Center, Dallas, TX 75246, USA.

Psychosomatics
|May 1, 1996
PubMed
Summary

Liver transplant recipients with alcohol issues had a low relapse rate into drinking, with most outcomes being favorable. Dual diagnosis patients experienced more significant relapses but overall medical outcomes were comparable.

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Area of Science:

  • Hepatology
  • Transplantation Surgery
  • Addiction Psychiatry

Background:

  • Alcohol abuse is a leading cause of liver cirrhosis.
  • Liver transplantation is a potential treatment for end-stage liver disease due to cirrhosis.
  • Assessing post-transplant outcomes in patients with a history of alcohol use is crucial.

Purpose of the Study:

  • To comprehensively evaluate liver transplant recipients with Laennec's cirrhosis and a history of alcohol abuse or dependency.
  • To determine the incidence and severity of alcohol relapse in this patient population.
  • To compare the medical outcomes of these patients with a control group.

Main Methods:

  • A 7-year longitudinal study of 68 liver transplant patients with Laennec's cirrhosis and alcohol issues.

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  • In-depth follow-up of patient drinking behavior and medical status.
  • Comparison with a control group of non-alcohol-related liver transplant recipients.

    • Main Results:

    • A 13% relapse rate into drinking was observed in the study sample (9 out of 68 patients).
    • Only one severe relapse with an adverse outcome occurred.
    • Four significant relapses were identified in patients with dual diagnoses.
    • Medical outcomes for the study group were comparable to the control group.

    Conclusions:

    • Liver transplantation can achieve favorable medical outcomes in carefully selected patients with alcohol-related cirrhosis.
    • Relapse into drinking is relatively uncommon, with most instances being non-severe.
    • Dual diagnosis may be a risk factor for more significant alcohol relapse post-transplantation.