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Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 19, 2013
Posttrauma symptoms in childhood leukemia survivors and their parents
M L Stuber1, D A Christakis, B Houskamp
1Child Psychiatry Division, Neuropsychiatric Institute, University of California at Los Angeles 90024-1759, USA.
Abstract:
This study used a self-report measure of posttraumatic stress (the Posttraumatic Stress Disorder Reaction Index) to evaluate 64 pediatric leukemia survivors age 7-19 years and their parents (mothers n = 63, fathers n = 42). Based upon normative data for the Reaction Index, 12.5% of the survivors, 39.7% of the mothers, and 33.3% of the fathers reported symptoms consistent with a severe level of posttraumatic stress. The data indicate that a substantial subset of pediatric cancer survivors and their parents experience severe symptoms that can be understood within a posttraumatic stress model. The data are discussed with regard to pediatric follow-up care for cancer survivors, as well as in terms of preventive steps that could be taken to lessen the traumatic aspects of pediatric cancer treatment.
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