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Diffuse and localised visual field defects to automated perimetry in primary open angle glaucoma
1Department of Ophthalmology, Henry Ford Health Sciences Center, Detroit, MI 48202, USA.
Eye (London, England)
|January 1, 1995
Summary
Diffuse visual field loss is present in early primary open angle glaucoma (POAG). This generalized loss decreases as visual field defects deepen, suggesting early diffuse loss progresses to localized defects in POAG patients.
Area of Science:
- Ophthalmology
- Visual field testing
- Glaucoma research
Background:
- The presence of diffuse visual field depression in primary open angle glaucoma (POAG) is debated.
- Localized visual field defects are considered characteristic of POAG.
Purpose of the Study:
- To determine the frequency of diffuse visual field loss in early POAG.
- To compare diffuse visual field loss with localized defects using automated static perimetry.
Main Methods:
- Twenty-five eyes of POAG patients underwent Humphrey Visual Field testing (Central 30-2 Threshold Test).
- STATPAC Total Deviation (TD) and Pattern Deviation (PD) plots were analyzed for test point abnormalities.
- Frequencies of TD and PD involvement were compared for all defects and deep defects (p < 1% and p < 0.5%).
Main Results:
- Total Deviation (TD) plots showed higher test point involvement than Pattern Deviation (PD) plots (41.5% vs 27.5%).
- This trend persisted for deep defects (20.1% vs 13.2%).
- Pure generalized sensitivity loss was less frequent for deep defects (6.9%) and increased with shallower defects.
Conclusions:
- A component of diffuse visual field sensitivity depression exists at all significant stages of POAG.
- This generalized loss diminishes as visual field defects become deeper.
- Early diffuse visual field loss in POAG may evolve into distinct localized defects in later stages.