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[20-year follow-up of hemophiliac patients infected with HIV]
J J Ayala Gaytán1, B G Camacho Mezquita, G Rico Bazaldúa
1Servicio de Infectología, Hospital de Especialidades, Monterrey, NL.
In 1986 we detected serum antibodies against HIV in twenty four patients of our group of 84 cases of moderate to severe hemophilics. Twenty were asymptomatic to the acquired immunodeficiency syndrome (AIDS). After seven years, only three (15%) remain asymptomatic and seventeen (85%) developed AIDS. The mean time of development of AIDS was 56 months. Of these patients, fourteen (70%) have died. The median survival between the onset of the disease and death was eleven months. Only four of the patients that died received zidovudin, and in them we observed a median survival of 32 months.
In 1986 we detected serum antibodies against HIV in twenty four patients of our group of 84 cases of moderate to severe hemophilics. Twenty were asymptomatic to the acquired immunodeficiency syndrome (AIDS). After seven years, only three (15%) remain asymptomatic and seventeen (85%) developed AIDS. The mean time of development of AIDS was 56 months. Of these patients, fourteen (70%) have died. The median survival between the onset of the disease and death was eleven months. Only four of the patients that died received zidovudin, and in them we observed a median survival of 32 months.