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[Hereditary gingival fibromatosis: a case report]
1Department of Dentistry, Chang Gung Memorial Hospital, Keelung, Taiwan, R.O.C.
Changgeng Yi Xue Za Zhi
|December 1, 1995
Summary
Hereditary gingival fibromatosis, a rare congenital condition, causes significant gum overgrowth. Surgical treatment and prosthetics effectively managed a patient, with no recurrence observed after one year.
Area of Science:
- Genetics and Oral Pathology
- Congenital Anomalies
- Periodontology
Background:
- Hereditary gingival fibromatosis (HGF) is a rare, inherited disorder.
- It presents as a dense, diffuse overgrowth of gingival tissue.
- The etiology remains largely undetermined.
Observation:
- A 30-year-old female presented with significant gingival enlargement affecting mastication and aesthetics.
- Family history revealed affected father, two sisters, and one daughter, suggesting autosomal dominant inheritance.
- Clinical examination showed fibrous enlargement without inflammation; microscopic analysis revealed increased connective tissue, collagen bundles, and fibroblasts.
Findings:
- Histopathology confirmed dense connective tissue with collagen and fibroblasts, and thickened epithelium with acanthosis and elongated rete pegs.
- Surgical gingivectomy with flap operation corrected the gingival overgrowth.
- Periodontal treatment included fixed partial dentures for missing molars.
Implications:
- Surgical intervention is effective for managing hereditary gingival fibromatosis.
- Long-term follow-up is crucial to monitor for recurrence.
- This case highlights the importance of considering genetic factors in gingival overgrowth.