Cell cycle in heteronuclear cell line VUP-1. I. Locomotion behaviour analysis

Time-lapse cinemicrography was used to study the locomotory activity of sperical cells of a heteronuclear cell line VUP-1 originating from a malignant melanoma of chorioidea. Migration of cells was followed during the entire cell cycle and locomotion was analyzed in relation to the population density and to the morphological and functional characteristics of the leading undulating membrane. The variations in cellular motility were related to the morphology of the membranes and their possible functional regulation.