Related Experiment Videos
Donor-to-host transmission of Mycoplasma hominis in lung allograft recipients
1Department of Medicine, University of Colorado Health Sciences Center, Denver 80262, USA.
Abstract:
Mycoplasma hominis is a significant pathogen in immunocompromised hosts, particularly organ transplant recipients. We describe two recipients of lung allografts from the same donor who had M. hominis pleuropulmonary infection during the immediate postoperative period. The most likely source of infection in these cases was the donor's respiratory tract. The slow-growing pinpoint colonies formed by M. hominis on routine bacterial culture medium may be easily overlooked and should be subcultured to mycoplasmal medium for definitive identification. The recommended management of this infection consists of drainage and antimicrobial therapy with tetracycline, clindamycin, or a fluoroquinolone. This report highlights the potential for M. hominis to be transmitted from donor to recipient during organ transplantation.
Insights
Mycoplasma hominis can infect lung transplant recipients, potentially transmitted from the donor. Early detection and treatment with specific antibiotics are crucial for managing this opportunistic infection.
Area of Science:
- Infectious Diseases
- Transplantation Immunology
- Microbiology
Background:
- Mycoplasma hominis is an opportunistic pathogen affecting immunocompromised individuals.
- Organ transplant recipients are particularly vulnerable to infections like M. hominis.
- Pleuropulmonary infections pose a significant risk in the immediate postoperative period.