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Colonization of a calcium phosphate/elastin-solubilized peptide-collagen composite material by human osteoblasts
A Rovira1, J Amedee, R Bareille
1CIDA (Centro de Investigacion y Desarrollo Aplicado sal) Centro Industrial Santiga, Barcelona, Spain.
Biomaterials
|August 1, 1996
Abstract:
The evaluation of the suitability of a new biomaterial as a possible substitute for bone tissue is described here. This biomaterial is based on calcium phosphate particles linked to an artificial connective matrix, the elastin-solubilized peptides (ESP) associated with type I and III collagens. This work demonstrates the feasibility of shaping this composite material into discs, describes its microstructural characteristics, and evaluates its capacity as a substrate for the proliferation of human osteoblasts without loss of their phenotypic expression.