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Polyarteritis nodosa and the antiphospholipid syndrome
R Schoonjans1, B Van Vlem, S Weyers
1Department of Gastroenterology, University Hospital, Ghent, Belgium.
Abstract:
We report a case of biopsy-proven polyarteritis nodosa (classic type in association with the antiphospholipid syndrome. Medium-sized arteriopathy was confirmed on visceral angiography. Elevated anticardiolipin antibodies were detected before initiating therapy with methylprednisolone and IV pulse cyclophosphamide. Rapid subsidence of symptoms correlated with a gradual normalisation of the erythrocyte sedimentation rate. After 6 months of therapy anticardiolipin antibodies were within normal limits. Only one similar case has been reported so far.
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