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Calcitonin gene-related peptide: vasoactive effects and potential therapeutic role
1Pharmacology Group, King's College, London, England.
General Pharmacology
|June 1, 1996
Abstract:
1. The cardiovascular biology of calcitonin gene-related peptide (CGRP) and the structurally related peptides amylin and adrenomedullin are briefly reviewed. 2. CGRP is a potent and long-lasting vasodilator; its possible role in disease, and the therapeutic potential of CGRP receptor agonists and antagonists is discussed.