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Published on: April 29, 2013
Temporal blood pressure patterns in children
1Department of Pediatrics, University of Texas-Houston, Medical School, USA.
Insights
Ambulatory blood pressure monitoring (ABPM) reveals early-life circadian blood pressure rhythms, crucial for hypertension management. Future pediatric research should focus on establishing normal values and optimizing treatment using ABPM.
Area of Science:
- Pediatric cardiology and chronobiology.
- Hypertension research and management.
Background:
- Circadian rhythms of blood pressure (BP) are established early in life.
- Understanding these rhythms is vital for managing pediatric hypertension.
Purpose of the Study:
- To highlight the importance of ambulatory blood pressure monitoring (ABPM) coupled with activity measurement.
- To outline future challenges and goals for pediatricians in assessing BP circadian rhythms.
Main Methods:
- Utilizing ABPM for objective measurement of blood pressure.
- Coupling BP determinations with objective measures of physical activity.
- Longitudinal studies of patients with varying forms of hypertension.
Main Results:
- ABPM is a powerful tool for hypertension management in children.
- ABPM aids in dissecting the determinants of hypertension.
- Objective activity measurement enhances BP assessment.
Conclusions:
- Establishing normal circadian BP values for children is a key future goal.
- ABPM can improve understanding of BP tracking and hypertension diagnosis.
- Optimizing antihypertensive medications and diagnosis based on end-organ damage are critical.
Abstract:
Circadian rhythms of BP are established early in life. The ABPM coupled with an objective measure of activity is a powerful tool for the management of hypertension and is a sensitive tool for the dissection of the determinants of hypertension. The challenge for pediatricians in the future includes such important goals as establishing normal values for the circadian assessment of BP for a growing child, coupling of BP determinations with activity, using the ABPM to better understand BP tracking, studying the rhythms of families using the ABPM, educating the medical and lay communities of the importance of rhythmic phenomena, studying longitudinally patients with varying forms of hypertension, using the ABPM to test and optimize antihypertensive medications, and determining the proper diagnosis of hypertension in children based on end-organ damage rather than surrogate measures.
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