Immunomodulation in transplantation with photopheresis

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M L Barr1

  • 1Division of Cardiothoracic Surgery, University of Southern California, Los Angeles 90033-4612, USA.

Artificial Organs
|August 1, 1996
PubMed

Photopheresis is a technique in which peripheral blood mononuclear cells, in the presence of a photoactivatable compound, are exposed extracorporeally to ultraviolet A light and reinfused, inducing a host autoregulatory immune response. Experimental work and ongoing clinical studies are helping to define the role of this novel, safe, and non-toxic immunomodulating technology in the field of transplantation.

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