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Stabilisation of vaccines using trehalose (Q-T4) technology
E M Gribbon1, S D Sen, B J Roser
1Quadrant Holdings Cambridge Limited, Vaccine Division, England.
Developments in Biological Standardization
|January 1, 1996
Abstract:
Efforts directed towards overcoming the problems of vaccine stability must take cost into consideration. One effective approach is the use of a simple stabilization technology applicable, in principle, to every type of vaccine candidate. Following the lead of Nature, the results in this paper show how such techniques based on trehalose have the potential to transform contemporary vaccine manufacture. The possibilities of novel delivery formats and vaccine combinations, currently not feasible, may now also be realised.