Consistency of repeated event-related potentials in clinically stable HIV-1-infected drug users

This study investigated the stability over time of delays in auditory event-related potentials (ERPs) caused by HIV-1 infection of the brain. ERPs were recorded at two time points from 17 former parenteral drug users (PDUs) and 8 non-PDU control subjects. There was no significant effect of time, and peak measures for the two visits were significantly correlated with each other. For both visits, N1 was delayed only for the seropositive stage IV subjects, whereas N2 was delayed for both seropositive groups. Group differences remained stable, confirming previously reported studies.