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Thyroid carcinoma as first manifestation of familial adenomatous polyposis
J A Stigt1, H F Vasen, K van der Linde
1Department of Internal Medicine, Drechtsteden Ziekenhuis Refaja, Dordrecht, Netherlands.
The Netherlands Journal of Medicine
|September 1, 1996
Abstract:
A 22-year-old female member of a family with familial adenomatous polyposis (FAP) presented with a thyroid nodule. Histology revealed a follicular carcinoma. The patient was on regular follow-up as part of the FAP screening program; 1.5 years after the thyroidectomy she appeared to have multiple adenomatous polyps in her colon and FAP was diagnosed. Thyroid-carcinoma is one of the extraintestinal manifestations of FAP and particularly women in the age of 25-35 years are at risk according to the literature.