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Related Experiment Videos

Gastrointestinal leiomyomas in a developing country

S Dasarathy1, G K Pandey, D K Bhargava

  • 1Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi.

Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation
|October 1, 1995
PubMed
Summary
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Gastrointestinal leiomyomas commonly cause bleeding and obstruction. Surgical excision is effective, though recurrence as leiomyosarcoma is possible in some patients.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Oncology

Background:

  • Gastrointestinal leiomyomas are rare mesenchymal tumors.
  • They can present with significant gastrointestinal bleeding or obstruction.

Purpose of the Study:

  • To analyze the clinical presentation, diagnosis, and outcomes of gastrointestinal leiomyoma patients.
  • To identify risk factors for recurrence.

Main Methods:

  • Retrospective study of 21 consecutive patients with gastrointestinal leiomyoma.
  • Diagnostic methods included barium meal, gastrointestinal endoscopy, and angiography.
  • Surgical excision was the primary treatment.

Main Results:

  • 18 patients (85.7%) presented with recurrent gastrointestinal bleeding.

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  • 3 patients (14.3%) experienced recurrent intestinal obstruction.
  • Stomach was the most common site, followed by ileum, jejunum, and duodenum.
  • Diagnosis was suggested preoperatively in 10 patients; 11 were diagnosed peroperatively.
  • Two patients experienced recurrence as leiomyosarcoma after excision.

    • Conclusions:

    • Gastrointestinal leiomyomas frequently manifest as bleeding or obstruction.
    • Surgical excision offers good outcomes, but vigilance for leiomyosarcoma recurrence is necessary.