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Related Experiment Videos

Surgical Infection Society position on vancomycin-resistant Enterococcus

J M Davis1, M M Huycke, C L Wells

  • 1Department of Surgery, Cornell University Medical College, New York, NY, USA.

Archives of Surgery (Chicago, Ill. : 1960)
|October 1, 1996
PubMed
Summary

Vancomycin resistance transfer to staphylococci is possible. Strict infection control is crucial for managing vancomycin-resistant Enterococcus (VRE) spread, as limiting vancomycin use alone is insufficient.

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Hospital Epidemiology

Background:

  • Vancomycin resistance in Enterococcus (VRE) poses a significant healthcare challenge.
  • Prolonged colonization with VRE is common, with more patients colonized than infected.

Purpose of the Study:

  • To highlight the risk of vancomycin resistance transfer to staphylococci.
  • To emphasize the critical role of infection control in managing VRE spread.

Main Methods:

  • Laboratory studies demonstrating vancomycin resistance transfer.
  • Clinical observations of VRE colonization and infection rates.
  • Analysis of infection control measure effectiveness.

Main Results:

  • Transfer of vancomycin resistance to staphylococci has been demonstrated in laboratory settings.

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  • Failure to implement and adhere to infection control protocols hinders VRE containment.
  • Restricting vancomycin use alone is unlikely to significantly reduce VRE colonization risk.

    • Conclusions:

    • Infection control measures are the primary defense against VRE spread within hospitals.
    • The global spread of VRE may be challenging to halt entirely.
    • Vigilant identification, isolation, and adherence to control measures are essential for VRE management.