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Updated: Aug 4, 2026

Expression Analysis of Mammalian Linker-histone Subtypes
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Characterization of the 55-kb mouse histone gene cluster on chromosome 3

Z F Wang1, R Tisovec, R W Debry

  • 1Department of Biology, University of North Carolina (UNC) at Chapel Hill 27599-7100, USA.

Genome Research
|August 1, 1996
PubMed

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Histone Variants at the Centromere

Histone variants are the histone proteins with structural and sequence variations. These variants may be regarded as “mutant” forms that replace their canonical histone counterparts in the nucleosomes. Specific post-translational modifications on the histone variants enable further chromatin complexity and regulate tissue-specific gene expression. The most common histone variants are from histone H2A, H2B, and linker histone H1 families. However, several variants of histone H3 variants are also...
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The extent of chromatin compaction can be studied by staining chromatin using specific DNA binding dyes. Under the microscope, the dense-compacted regions that take up more dye are called heterochromatin. Heterochromatin is further classified into two forms – constitutive heterochromatin and facultative heterochromatin.
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