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Autoimmune polyendocrinopathy--candidiasis--ectodermal dystrophy (APECED)
1Children's Hospital, University of Helsinki, Finland.
Abstract:
APECED, an autosomal recessive disease manifests itself as a widely variable combination of three groups of components: 1) autoimmune destruction of tissues, predominantly endocrine glands, 2) chronic superficial candidiasis, and 3) ectodermal dystrophy. Clinical and basic information obtained from Finnish series of 72 patients is reviewed.