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Related Experiment Videos

Baclofen for chronic hiccups

B R Johnson1, R L Kriel

  • 1Department of Pediatrics, Gillette Children's Hospital and Health Partners, St. Paul/Minneapolis, Minnesota, USA.

Pediatric Neurology
|July 1, 1996
PubMed
Summary
This summary is machine-generated.

Baclofen effectively treated chronic hiccups in a young adult, resolving a debilitating 3-year condition. Dosage adjustments managed recurrences, offering a potential therapeutic strategy for intractable hiccups.

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Area of Science:

  • Neurology
  • Gastroenterology

Background:

  • Chronic hiccups are rare but can significantly impair quality of life.
  • Few successful interventions are documented for persistent hiccups.

Observation:

  • A young adult experienced severe, near-continuous hiccups for three years post-gastrostomy and Nissen fundoplication.
  • The condition was debilitating and resistant to prior treatments.

Findings:

  • Baclofen treatment initiated within weeks led to the cessation of hiccups.
  • Subsequent recurrences of hiccups responded favorably to increased baclofen dosage.

Implications:

  • Baclofen represents a promising therapeutic option for managing chronic hiccups.
  • This case highlights the potential efficacy of baclofen in refractory hiccup cases.