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Inflammatory opacities of the vitreous in rifabutin-associated uveitis
M J Chaknis1, S E Brooks, K T Mitchell
1Department of Ophthalmology, Medical College of Georgia, Augusta 30912, USA.
Purpose:
To describe rifabutin-associated uveitis with opacities in the inferior and posterior vitreous in three patients with acquired immunodeficiency syndrome.
Method:
Case reports of the three patients are presented.
Results:
The patients, who were being treated with rifabutin and fluconazole, developed anterior and posterior uveitis. The posterior uveitis was characterized by white-yellow inflammatory opacities located in the inferior and posterior vitreous. Discontinuation of rifabutin and the start of topical corticosteroid therapy resulted in improvement of the uveitis and visual acuity.
Conclusion:
Recognition of rifabutin-associated uveitis with opacities in the inferior and posterior vitreous may prevent unnecessary invasive diagnostic and therapeutic procedures.