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Hypoxemia associated with cimetidine therapy in a newborn infant
J Kuint1, N Linder, B Reichman
1Department of Neonatology, The Chaim Sheba Medical Center, Israel.
American Journal of Perinatology
|July 1, 1996
Abstract:
Cimetidine therapy used for the treatment of gastric bleeding due to tolazoline therapy in a newborn infant was temporally associated with episodes of severe hypoxemia. It appears likely that the histamine H2 receptor blocked by cimetidine obviated the pulmonary vasodilator effect of tolazoline therapy.