Related Experiment Videos
Taxol-induced acral erythema
D de Argila1, J D Dominguez, L Iglesias
1Department of Dermatology, Hospital Universitario Doce de Octubre, Madrid, Spain.
Dermatology (Basel, Switzerland)
|January 1, 1996
Abstract:
Chemotherapy-induced acral erythema is a peculiar localized cutaneous response to several chemotherapeutic agents, mostly antimetabolites. Taxol is a recently developed antineoplastic drug that acts on the mitotic spindle and does not interfere with nucleic acid synthesis. We describe the first case of taxol-induced acral erythema and report on additional data concerning the pathogenesis of this kind of toxic eruptions.