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Binding of pyridine derivatives to cytochrome P-450

J L Born, D Vaughn

Journal of Pharmaceutical Sciences

|July 1, 1977

Abstract:

The spectral binding constants, Ks, of pyridine, methylpyridine, and dimethylpyridines were determined. The Ks values of the compounds were discussed in terms of mechanisms of possible bonding to cytochrome P-450.

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