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Chagas' disease after bone marrow transplantation
J Altclas1, G Jaimovich, V Milovic
1Instituto de Criopreservación y Transplante de Médula Osea, IMA, Buenos Aires, Argentina.
Bone Marrow Transplantation
|August 1, 1996
Insights
Chagas' disease, caused by Trypanosoma cruzi, affects millions in Latin America. Immunocompromised patients, like bone marrow transplant (BMT) recipients, face risks of reactivation or transfusion-transmitted infection, as illustrated by this acute case.
Area of Science:
- Infectious Diseases
- Hematology
- Transplantation Immunology
Background:
- Chagas' disease, caused by the parasite Trypanosoma cruzi, is a significant public health concern endemic to Latin America, with an estimated 16–18 million infected individuals.
- Immunocompromised populations, particularly bone marrow transplant (BMT) recipients, are susceptible to Chagas' disease reactivation or transfusion-transmitted infections.
- The clinical presentation and management of Chagas' disease in the context of BMT are critical areas of study due to potential severe outcomes.
Abstract:
Chagas' disease is caused by Trypanosoma cruzi. It is endemic in Latin America where 16 to 18 million people are infected. Immunocompromised patients such as BMT recipients are at risk of Chagas' disease either due to reactivation or transfusion. We report a case of acute Chagas' disease in the setting of BMT.