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Cutaneous angiomyolipoma

J F Val-Bernal¹, C Mira

¹Anatomical Pathology Department, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain.

Journal of Cutaneous Pathology

|August 1, 1996

Summary

This summary is machine-generated.

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Extrarenal angiomyolipomas are rare skin tumors. This case report details a unique ear lobe angiomyolipoma, highlighting differences from renal forms.

Area of Science:

Dermatology
Pathology
Oncology

Background:

Extrarenal angiomyolipomas are uncommon mesenchymal tumors.
Cutaneous angiomyolipomas present distinct characteristics compared to their renal counterparts.

Observation:

A case of a 49-year-old male with an angiomyolipoma on the right ear lobe is presented.
Pathologic examination revealed a well-circumscribed 2 cm subcutaneous nodule.
Immunohistochemistry confirmed tumor components, with negative HMB-45 reactivity.

Findings:

A review of 13 cases (including this one) showed a patient age range of 33-77 years (mean 53.6).
The male to female ratio was 11:1, with tumors typically solitary, asymptomatic, and noninvasive.
Common locations include acral skin and the ear; tuberous sclerosis signs were absent in all cases.

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Implications:

Cutaneous angiomyolipomas differ from renal forms in sex predominance, clinical associations, and HMB-45 immunoreactivity.
Distinguishing these lesions from other mesenchymal tumors relies on established histologic criteria.
This case contributes to understanding the spectrum of angiomyolipomas in extrarenal locations.