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Hepatocyte growth factor in nephronophthisis-medullary cystic disease complex
N Yorioka1, Y Taniguchi, K Yamashita
1Second Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
Pediatric Nephrology (Berlin, Germany)
|August 1, 1996
Abstract:
A 13-year-old Japanese girl presented with severe anemia and renal dysfunction. The nephronophthisis-medullary cystic disease complex was diagnosed from the results of renal biopsy and a family study. Immunohistochemical detection of hepatocyte growth factor in the epithelial cells of dilated renal tubules suggested that it may have a role in the development of the tubular cystic changes which are characteristic of this disease.