Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nutrient malassimilation following total gastrectomy

R Brăgelmann1, U Armbrecht, D Rosemeyer

  • 1Dept. of Gastroenterology, Academisch Hospital Maastricht, The Netherlands.

Scandinavian Journal of Gastroenterology. Supplement
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transesophageal echocardiography to assess embolic risk in patients with atrial fibrillation. ELAT Study Group. Embolism in Left Atrial Thrombi.

Annals of internal medicine·1998
Same author

[Symptomatic local therapy of the uncomplicated common cold. Multicenter controlled study of the effectiveness of an antiseptic lozenge].

Fortschritte der Medizin·1998
Same author

Pre-steady state of reaction of nucleoside diphosphate kinase with anti-HIV nucleotides.

The Journal of biological chemistry·1998
Same author

Role of Mg2+ in nucleoside diphosphate kinase autophosphorylation.

Archives of biochemistry and biophysics·1998
Same author

Subdural hygromas after bone marrow transplantation: results of a prospective study.

Transplantation·1998
Same author

[Hydro-CT in detection and staging of pancreatic carcinoma].

Der Radiologe·1998
Same journal

Abstract from the 41st Nordic Gastroenterology Congress, 8-11 June 2010, Copenhagen, Denmark.

Scandinavian journal of gastroenterology. Supplement·2010
Same journal

Abstracts from the XL Nordic Meeting of Gastroenterology, June 8-11, 2009, Stavanger, Norway.

Scandinavian journal of gastroenterology. Supplement·2009
Same journal

Abstracts of the 39th Nordic Meeting of Gastroenterology, 30th Nordic Meeting of Digestive Endoscopy, 18th Nordic Meeting of Gastrointestinal Motility, and the Annual Endoscopy/Gastroenterology Nurses'/Assistants' Meeting Post-graduate course, 4-6 June 2008, Helsinki, Finland.

Scandinavian journal of gastroenterology. Supplement·2008
Same journal

Abstracts from the XXXVIII Nordic Meeting of Gastroenterology, XXIX Nordic Meeting of Digestive Endoscopy, XVII Nordic Meeting of Gastrointestinal Motility, 6-9 June 2007, Reykjavik, Iceland.

Scandinavian journal of gastroenterology. Supplement·2007
Same journal

Abstracts of the XXXVII Nordic Meeting of Gastroenterology, 3-5 May 2006, Vasteras, Sweden.

Scandinavian journal of gastroenterology. Supplement·2006
Same journal

Novel approaches in the outpatient care of patients with chronic inflammatory bowel disease.

Scandinavian journal of gastroenterology. Supplement·2006
See all related articles

Total gastrectomy frequently causes abdominal symptoms and malassimilation. Shortened small-bowel transit and pancreatic enzyme dyssynchrony are key factors contributing to these post-surgical complications.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Digestive Physiology

Background:

  • Total gastrectomy for gastric malignancy can lead to significant post-operative complications.
  • Understanding the pathophysiology of these symptoms is crucial for patient management.

Purpose of the Study:

  • To determine the prevalence and underlying mechanisms of abdominal symptoms, malnutrition, and malassimilation following total gastrectomy.
  • To investigate objective parameters associated with malassimilation.

Main Methods:

  • Evaluated 174 patients who underwent potentially curative total gastrectomy for gastric cancer.
  • Assessed subjective symptoms and objective malassimilation parameters, including body mass index, nutrient deficiencies, and small-bowel transit time.

Related Experiment Videos

Main Results:

  • 86% of patients experienced abdominal symptoms.
  • Despite adequate calorie intake, mean body mass index decreased.
  • Prevalence of anemia (46%), sideropenia (31%), and esophagitis (26%) was noted.
  • Significant fat malassimilation (14.8%) and bacterial overgrowth (37.7%) were observed.
  • Shortened small-bowel transit occurred in 21.7% of patients.

Conclusions:

  • Malassimilation after total gastrectomy is multifactorial.
  • Shortened small-bowel transit and pancreatic enzyme dyssynchrony are major contributors to malassimilation.
  • Further research into optimizing digestive function post-gastrectomy is warranted.