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Campylobacter bacteremia in children
R P Reed1, I R Friedland, F O Wegerhoff
1Shongwe Mission Hospital, South Africa.
The Pediatric Infectious Disease Journal
|April 1, 1996
Summary
Children with malnutrition are at higher risk for Campylobacter jejuni bacteremia, a serious infection. Prompt management is crucial for these vulnerable pediatric patients.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
Background:
- Campylobacter bacteremia is a significant concern in children, particularly in resource-limited settings.
- Understanding the clinical profile and risk factors is essential for effective management.
Observation:
- A study reviewed 19 cases of Campylobacter bacteremia in children from impoverished South African communities.
- Malnutrition was prevalent, with 84% of affected children exhibiting malnutrition, 13 severely.
- Fever was present in 68% of cases; 21% did not present with diarrhea.
Findings:
- All isolates were identified as Campylobacter jejuni.
- The case fatality rate was 16%, with no clear influence of aminoglycoside treatment noted.
Implications:
- Malnutrition may increase susceptibility to gastrointestinal Campylobacter jejuni infections.
- Immunodeficiency and compromised intestinal mucosa due to malnutrition elevate the risk of bacteremia.
- Campylobacter jejuni bacteremia is a life-threatening condition requiring appropriate medical intervention.