Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Drug-induced vasculitis

L H Calabrese1, G F Duna

  • 1Department of Rheumatic and Immunologic Disease, Cleveland Clinic Foundation, OH 44195, USA.

Current Opinion in Rheumatology
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Intersection of COVID-19 and Autoimmunity: What is Our Current Understanding?

Pathogens & immunity·2021
Same author

Treatment of psoriasis with ustekinumab in a patient with HIV-related Kaposi sarcoma.

Clinical and experimental dermatology·2018
Same author

ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Soluble immune effector molecules [II]: agents targeting interleukins, immunoglobulins and complement factors).

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2018
Same author

Rheumatic immune-related adverse events of checkpoint therapy for cancer: case series of a new nosological entity.

RMD open·2017
Same author

Menstrual Abnormalities, Nutritional Patterns, and Body Composition in Female Classical Ballet Dancers.

The Physician and sportsmedicine·2016
Same author

AIDS and Athletes.

The Physician and sportsmedicine·2016
Same journal

New approaches to the management of cutaneous lupus.

Current opinion in rheumatology·2026
Same journal

"Updates in chronic nonbacterial osteomyelitis: emerging insights across the age spectrum".

Current opinion in rheumatology·2026
Same journal

Difficult-to-treat, complex-to-manage, treatment-refractory spondyloarthritis: semantics or substance?

Current opinion in rheumatology·2026
Same journal

Update on IgA nephropathy: implications for treatment in IgA vasculitis: a guide for rheumatologists.

Current opinion in rheumatology·2026
Same journal

Polyarticular juvenile idiopathic arthritis: insights from genetic studies on disease risk and pathogenesis.

Current opinion in rheumatology·2026
Same journal

Immune dysregulation in children with Down syndrome: clinical implications and emerging therapies.

Current opinion in rheumatology·2026
See all related articles

Drug-induced vasculitis encompasses diverse, poorly understood conditions. Early identification and drug cessation are crucial for managing these potentially severe inflammatory disorders.

Area of Science:

  • Rheumatology
  • Immunology
  • Pharmacology

Background:

  • Drug-induced vasculitis presents diverse clinical and pathological features.
  • Ambiguous terminology like hypersensitivity vasculitis complicates diagnosis and understanding.
  • These conditions range from mild to life-threatening and are associated with various medications, including newer biologic agents.

Purpose of the Study:

  • To review the spectrum of drug-induced vasculitis.
  • To highlight the diagnostic challenges and clinical variability.
  • To emphasize the importance of drug withdrawal in management.

Main Methods:

  • Literature review of drug-induced vasculitis.
  • Analysis of clinical presentations and pathological findings.

Related Experiment Videos

  • Discussion of diagnostic criteria and therapeutic approaches.

    • Main Results:

    • Drug-induced vasculitis involves varied presentations, from self-limiting to fatal outcomes.
    • Central nervous system vasculitis is a significant manifestation linked to drug use.
    • Newer drug classes, such as biologic response modifiers, are implicated.

    Conclusions:

    • Drug-induced vasculitis is a complex entity requiring careful diagnosis.
    • Removal of the causative agent is often associated with clinical improvement.
    • Further research is needed to clarify underlying mechanisms and standardize terminology.