Rheumatologic manifestations of renal disease

The rheumatologic manifestations of renal disease are commonly encountered and include crystal deposition disease and renal osteodystrophy. In addition, renal transplantation carries important rheumatologic manifestations. Basic calcium phosphate crystal deposition remains an important source of morbidity in renal disease, but it can be largely prevented. Early preventive measures and use of biochemical markers for assessment allow effective management of renal osteodystrophy. Effective treatment is available for the acute bone pain syndrome seen after transplantation, and the natural history of osteonecrosis in such patients may be more benign than previously considered, thus affecting current management schemes for this complication.