Immediate outcome following coronary angioplasty. A contemporary single centre audit
P N Ruygrok1, P P De Jaegere, J J Verploegh
1Department of Cardiology, Erasmus University, Rotterdam, Netherlands.
Insights
Coronary angioplasty shows significant rates of angiographic failure and complications like death and myocardial infarction. While emergency bypass surgery decreases, overall adverse event rates remain high.
Area of Science:
- Cardiology
- Interventional Cardiology
- Clinical Outcomes Research
Background:
- Coronary angioplasty is a common procedure for treating coronary artery disease.
- Assessing in-hospital outcomes is crucial for procedural refinement and patient safety.
Purpose of the Study:
- To evaluate the in-hospital outcomes of coronary angioplasty procedures.
- To determine rates of angiographic success and clinical complications.
- To identify factors associated with adverse outcomes.
Main Methods:
- Retrospective analysis of 970 coronary angioplasty procedures performed between October 1993 and October 1994.
- Data collected on clinical, procedural, and angiographic variables.
- Statistical analysis using chi-square tests and univariate/multivariate models.
Main Results:
- Angioplasty was performed for stable angina (49%), unstable angina (42%), and emergency indications (9.5%).
- In-hospital complications included 1.0% mortality, 7.3% myocardial infarction, and 2.0% emergency bypass surgery.
- Factors associated with angiographic failure included age >60 and type C lesions. Complications increased with age >60, unstable angina, low ejection fraction, new devices, and dissection.
Conclusions:
- Coronary angioplasty continues to have significant rates of angiographic failure and clinical complications.
- Mortality, infarction, and abrupt closure rates have shown little reduction over 15 years.
- Emergency coronary artery bypass surgery rates are decreasing, potentially due to improved bailout techniques like stenting.
Unlabelled:
To study the in-hospital outcome of all coronary angioplasty procedures performed in a single centre over a 1 year period, with regard to angiographic success and the clinical complications of death, myocardial infarction, emergency coronary bypass surgery and abrupt coronary occlusion necessitating reintervention.
Methods:
One thousand one hundred and thirty-three lesions were treated in 970 procedures in 799 patients between October 1993 and October 1994. Clinical, procedural, angiographic and outcome data were entered into a dedicated computer data-base and variables tested with respect to outcome using the chi-square test and univariate and multivariate analysis techniques.
Results:
Angioplasty was performed for stable angina in 473 (49%) patients, unstable angina in 410 (42%) and 80 procedures were emergency--primary myocardial infarction in 44 (4.5%), shock in two, abrupt closure in 34 (3.5%) and other indications in seven patients. There were 10 (1.0%) deaths and 71 (7.3%) patient were documented to have suffered a myocardial infarction as a result of angioplasty. Nineteen (2.0%) patients underwent emergency coronary artery bypass surgery. Age >60 and a type C lesion were found to be associated with angiographic failure. The chance of a complication was increased if the patient was aged >60 years, suffered unstable angina, had an ejection fraction <50%, was treated with a new device or suffered a significant dissection.
Conclusion:
Despite refinement in techniques and increased experience, coronary angioplasty retains a significant associated chance of angiographic failure. The complication rate remains significant and there has been little reduction in mortality, infarction and abrupt closure rates over the last 15 years. The requirement for emergency coronary artery bypass surgery appears to be diminishing with the introduction of improved bail-out techniques, in particular intracoronary stenting.
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