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Malignant hyperthermia in a 3-month-old infant: a case report
First described in 1960, malignant hyperthermia (MH) is a relatively rare disorder of muscle metabolism triggered by specific anesthetic agents and presenting as a rapidly evolving intraoperative crisis. The syndrome is more prevalent among children (1/15,000 exposures to anesthesia) than adults (1/50,000 exposures), but has not been thought to occur in children younger than 1 year of age. This is a case report of a 3-month-old, 4.85 kg white male infant who developed MH while undergoing repair of a right inguinal hernia. The case is unique not only with respect to the age of the patient but also with the extremely elevated creatine phosphokinase (CPK) 13 hours postoperatively.
First described in 1960, malignant hyperthermia (MH) is a relatively rare disorder of muscle metabolism triggered by specific anesthetic agents and presenting as a rapidly evolving intraoperative crisis. The syndrome is more prevalent among children (1/15,000 exposures to anesthesia) than adults (1/50,000 exposures), but has not been thought to occur in children younger than 1 year of age. This is a case report of a 3-month-old, 4.85 kg white male infant who developed MH while undergoing repair of a right inguinal hernia. The case is unique not only with respect to the age of the patient but also with the extremely elevated creatine phosphokinase (CPK) 13 hours postoperatively.