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Synthesis of a compound soluble in organic solvents from deoxycytidine triphosphate in permeabilized normal human
Molecular and Cellular Biochemistry
|July 5, 1977
Abstract:
Normal human lymphocytes may be rendered permeable to deoxynucleoside triphosphates. When [3H]dCTP is furnished to permeabilized lymphocytes tow compounds are formed: DNA and a compound soluble in organic solvents. [3H]dCTP incorporation is higher in stimulated lymphocytes than in unstimulated cells. Some characteristics of the system are reported.