Related Experiment Videos
Cardiac manifestations in dermato-polymyositis
L Gonzalez-Lopez1, J I Gamez-Nava, L Sanchez
1Department of Medicine, Hospital General Regional #45, IMSS, Guadalajara, Mexico.
Clinical and Experimental Rheumatology
|July 1, 1996
Summary
Subclinical heart abnormalities are common in dermato-polymyositis patients, with left ventricular diastolic dysfunction frequently observed. Early cardiac assessment is recommended for timely intervention.
Area of Science:
- Cardiology
- Rheumatology
- Internal Medicine
Background:
- Dermato-polymyositis (DM/PM) is an inflammatory myopathy that can affect multiple organ systems.
- Cardiac involvement in DM/PM is often subclinical and underdiagnosed.
Purpose of the Study:
- To investigate the prevalence and types of functional and anatomic cardiac abnormalities in patients with DM/PM.
- To identify specific cardiac manifestations associated with DM/PM.
Main Methods:
- A cohort of 32 patients with DM/PM underwent comprehensive cardiac evaluation.
- Assessments included symptom questionnaires, physical exams, EKG, Holter monitoring, and color Doppler flow (CDF) studies.
- CDF evaluated for left ventricular diastolic dysfunction (LVDD), hyperdynamic heart, mitral valve prolapse, and endomyocardial fibrosis.
Main Results:
- Over half of the patients exhibited electrical disturbances on EKG or Holter monitoring.
- Left ventricular diastolic dysfunction (LVDD) was detected in 42% of patients.
- Hyperdynamic heart was observed in 15% of patients; no mitral valve prolapse was found.
Conclusions:
- Subclinical cardiac abnormalities are frequent in DM/PM patients.
- LVDD is a common finding in this population.
- Routine cardiac assessment is crucial for detecting and managing DM/PM-related heart conditions.