Related Experiment Video
Updated: Aug 13, 2026

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Published on: December 4, 2020
Childhood vulvovaginitis and vaginal discharge in general practice
1Roborough Surgery, Plymouth, UK.
Insights
Childhood vulvovaginitis, often caused by mixed fecal organisms and poor hygiene, is common in general practice. Treatments like oral antibiotics are effective, with rare links to serious issues like sexual abuse.
Area of Science:
- Pediatrics
- General Practice
- Gynecology
Background:
- Vulvovaginitis is a common condition in premenarchal girls presenting in general practice.
- Understanding its causes, clinical presentation, and treatment response is crucial for effective management.
Purpose of the Study:
- To investigate the etiology, clinical features, and treatment outcomes of childhood vulvovaginitis in a general practice setting.
- To identify common causative agents and assess treatment efficacy.
Main Methods:
- A longitudinal survey of 42 premenarchal girls with vulvovaginitis or vaginal discharge was conducted.
- Methods included clinical evaluation, microbiological assessment (urine and vaginal swabs), and symptom resolution tracking.
Main Results:
- Non-specific vulvovaginitis with mixed bacterial flora, linked to poor hygiene, was most common.
- Specific bacteria (e.g., Streptococcus pyogenes) were found in 10 cases; no Candida was isolated.
- Oral antibiotics were effective for both mixed and single organism infections; topical estrogen was effective only for mixed infections.
Conclusions:
- Childhood vulvovaginitis is frequent in general practice, typically involving mixed fecal organisms.
- Serious causes like sexual abuse or foreign bodies are rarely identified.
- Effective management often involves addressing hygiene and appropriate antibiotic therapy.
Objective:
This study aims to examine the aetiology, clinical features and response to treatment of childhood vulvovaginitis in general practice.
Method:
A longitudinal survey of consecutive premenarchal patients presenting with vulvovaginitis and/or vaginal discharge in the course of normal consultations with a general practitioner was conducted in a semi-rural, group general practice with 11,000 patients in Plymouth, UK. Forty-two premenarchal girls with vaginal inflammation or discharge were surveyed, with main outcome measures being clinical evaluation, microbiological assessment of urine and vaginal swabs, and patients' and parents' assessments of resolution and relapse of symptoms.
Results:
Non-specific vulvovaginitis with mixed bacterial flora, associated with poor hygiene and atrophic vaginal mucosa, was the commonest cause; specific bacteria were found in 10 out of 42 cases, including six of Streptococcus pyogenes. No candida was isolated. Treatment with topical oestrogen cream was effective only with mixed infection, oral antibiotics were effective in both mixed and single organisms. No evidence of sexual abuse nor foreign body was found.
Conclusion:
Childhood vulvovaginitis is not uncommon in general practice, is usually associated with mixed growth of faecal organisms, and is seldom due to serious causes such as sexual abuse or foreign body.
Related Concept Videos
Disorders of the Female Reproductive System
Sexually Transmitted Infections
Microbiota of the Urogenital Tract
Genital Herpes
Candidiasis
Trichomoniasis

